CeraVe and L’Oréal Groupe have received the prestigious Applied Research Award at the 35th International Federation of Societies of Cosmetic Chemists (IFSCC) Congress. As this marks a major breakthrough in the study of scalp biology and dandruff, read along to learn more.
This award-winning research by CeraVe and L’Oréal Groupe is the first of its kind. It compared dandruff-affected and healthy scalps to deliver the most comprehensive understanding of dandruff pathophysiology to date. The study assessed clinical symptoms, ceramide profiles, microbiome composition, and inflammatory markers. These were studied across over 200 participants from diverse racial and ethnic backgrounds.
The findings significantly advance scalp science. They deepen understanding of the scalp barrier, the microbiome, and how these elements interact to influence dandruff.
Expanding on previous microbiome research
This study builds on earlier microbiome work published in the Journal of Drugs in Dermatology. This new and previously unpublished study goes a step further. It explores ethnic variations and provides the first-ever functional analysis of the scalp microbiome.
Beyond studying Malassezia — the fungus traditionally linked to dandruff — researchers identified new microbial targets associated with inflammation and scalp imbalance. These insights open doors for more diverse and personalized dandruff treatments.
Key discoveries
The research revealed several major findings:
- Bacterial Drivers: Staphylococcus aureus (S. aureus) and Staphylococcus capitis (S. capitis) were more abundant in dandruff across all ethnic groups.
- Strong S. aureus Link: A clear positive correlation emerged between S. aureus abundance and dandruff severity.
- Virulence Factors: Dandruff scalps showed elevated virulence factor gene levels, especially in Latin/Hispanic and Asian American groups.
- Ethnic Variations: While Malassezia levels were higher in dandruff across most groups, Malassezia globosa was found predominantly on healthy scalps.
Redefining dandruff science
By examining the scalp microbiome across ethnicities and identifying microbial contributors beyond Malassezia, this study marks a paradigm shift in dandruff research. It highlights the need for personalised care approaches. It also reinforces L’Oréal and CeraVe’s shared mission to advance dermatological science for all skin and scalp types.
From the leadership desk
Gene Colón, Global Senior Vice President, Medical Affairs & Communications for CeraVe at L’Oréal:
“Receiving the IFSCC Applied Research Award is a testament to our joint commitment to scientific innovation and understanding the intricate biology of skin and scalp barrier health. This game-changing research moves beyond the traditional view of dandruff to highlight the role of ceramide deficiency and scalp barrier dysfunction, the critical bacterial component and the impact of ethnicity. It significantly expands our scientific understanding, rooted in our foundational ceramide science, offering new perspectives and possibilities for future innovations.”
Qian Zheng, Ph.D., Senior Vice President of Advanced Research for North America and Global Head for Regenerative Beauty at L’Oréal Groupe:
“This recognition reflects L’Oréal’s Research & Innovation teams’ leadership in scientific innovation and our mission to pioneer skin, hair, and scalp science continuously. By integrating microbiome research with barrier biology through an inclusive lens, our teams are pioneering new approaches to scalp care – translating deep biological insights into targeted, effective solutions for consumers around the world.”
Representational Banner Image | Credits: Freepik